Artikel Jurnal Hypoglycemic Activity and Pancreas Protection of Combination Juice of Mengkudu (Morinda citrifolia Linn.) Juice and Temulawak (Curcuma xanthorrhiza Roxb.) Juice on Streptozotocin-Induced Diabetic Rats

Abstract : Noni fruit
contains scopoletin and temulawak rhizome contains curcumin have been observed
because they have strong antioxidant activity and they were used traditionally
antidiabetic as This research aimed to evaluate the effect of antihyperglycemic
and pancreas protection of juice combination of Noni fruit juice (MFJ) and
Curcuma rhizome juice (TRJ) on diabetes rats which were inducted with
streptozotocin (STZ). Rats were grouped into 7 groups, each of group consists
5 rats. Each group was treated according to 28 days except for a normal
group of rats. Rats taken blood from the plexus retroorbitalis for examination
of blood glucose levels every week. On the last day, rats blood was examined
for malondialdehyde (MDA) levels. After that the rats were turned off for
examination of pancreatic morphological conditions. The results showed that diabetic
rats given MFJ-TRJ combination juice experienced a significant decrease in
blood glucose levels, a significant reduction in MDA levels and improvement
pancreas morphology when compared with the negative control group. The
conclusion of this research was the combination of juice of MFJ-TRJ juice can
decreased blood glucose level, decreased MDA level and can be improved pancreas
morphology condition.

Keywords : hypoglycemic,
pancreas protection, combination of juice, noni, temulawak

Author : Bilal Subchan Agus
Santoso, Sudarsono, Agung Endro Nugroho, Yosi Bayu Murti

Journal Code: jpfarmasigg180004



Related Articles:

Tinggalkan pesan "Artikel Jurnal Hypoglycemic Activity and Pancreas Protection of Combination Juice of Mengkudu (Morinda citrifolia Linn.) Juice and Temulawak (Curcuma xanthorrhiza Roxb.) Juice on Streptozotocin-Induced Diabetic Rats"

Penulis: 
    author